The story takes place in Skull Creek, an 1870s Montana gold camp. Dr. Joseph Frail (Cooper) arrives, setting out his shingle near the camp's boom-or-bust hubbub of adventurers, ladies of fortune, mountain men and just plain decent folks. As skilled with a six-gun as with a scalpel, Frail will need both. A tragic past shadows his days. The treachery of the mob clouds his future. A determined immigrant (Maria Schell), a shifty-eyed miner (Karl Malden) and a hellfire preacher (debuting George C. Scott) figure prominently in Frail's showdown with fate. Prominent, too, is the breathtaking countryside. Here the mountains are imposing. And a man alone looms ever taller.